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Science 28 August 1964:
Vol. 145. no. 3635, pp. 932 - 934
DOI: 10.1126/science.145.3635.932
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Articles

Fluoride: Its Effects on Two Parameters of Bone Growth in Organ Culture

William R. Proffit 1 and James L. Ackerman 1

1 Oral and Pharyngeal Development Section, National Institute of Dental Research, Bethesda, Maryland 20014

Bones of the forepaws of young rats were subjected to varying concentrations of fluoride ions in organ culture. The formation of DNA and protein synthesis were evaluated by measurements of the uptake of tritiated thymidine and C14-labeled proline. Fluoride concentrations as high as 10 to 20 parts per million had no demonstrable effect in vitro on these basic parameters of skeletal growth


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Fluoride Protection of Bones and Teeth.
R. F. Sognnaes (1965)
Science 150, 989-993
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Science. ISSN 0036-8075 (print), 1095-9203 (online)