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Science 21 August 1964:
Vol. 145. no. 3634, pp. 821 - 822
DOI: 10.1126/science.145.3634.821

Articles

Macroglobulin from Human Plasma Which Forms an Enzymaticaliy Active Compound with Trypsin

John W. Mehl 1, William O'Connell 1, and John DeGroot 1

1 Department of Biochemistry, University of Southern California School of Medicine, Los Angeles

The protein from human plasma which forms an enzymatically active complex with trypsin and is able to protect trypsin from inhibition by soybean trypsin inhibitor has been shown to be an agr2-macroglobulin. It was obtained from the lipid-poor euglobulin of Cohn Fraction III-0, and appears to be closely related to the 19S-glycoprotein or agr2macroglobulin


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Hyper-Alpha-2-Macroglobulinemia in Narcotic Addicts.
N. F. ADHAM, M. K. SONG, and B. F. ENG (1978)
Ann Intern Med 88, 793-795
   Abstract »    PDF »
Exocrine Function of the Pancreas: Reappraisal of Some Physiological and Biochemical Principles.
B. J. Haverback (1965)
JAMA 193, 279-283
   Abstract »    PDF »
Hereditary Deficiency of Serum agr1-Antitrypsin.
F. Kueppers, W. A. Briscoe, and A. G. Bearn (1964)
Science 146, 1678-1679
   Abstract »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)