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Science 21 August 1964:
Vol. 145. no. 3634, pp. 819 - 821
DOI: 10.1126/science.145.3634.819

Articles

Nucleic Acid Metabolism in L Cells Infected with a Member of the Psittacosis Group

Esther M. Schechter 1, Ilse I. E. Tribby 1, and James W. Moulder 1

1 Department of Microbiology, University of Chicago, Chicago, Illinois

Multiplication of the meningopneumonitis agent in the cytoplasm of L cells in suspension culture is accompanied by parallel increases in cytoplasmic DNA, RNA, and phospholipid. Synthesis of RNA and phospholipid in infected cells is inhibited at the height of meningopneumonitis multiplication, but nuclear DNA synthesis is inhibited earlier and to a greater degree





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Science. ISSN 0036-8075 (print), 1095-9203 (online)