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Science 14 August 1964:
Vol. 145. no. 3633, pp. 714 - 715
DOI: 10.1126/science.145.3633.714
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Articles

Staphylococcal Alpha-Hemolysin: Detection on the Erythrocyte Membrane by Immunofluorescence

Albert S. Klainer 1, Morton A. Madoff 1, Louis Z. Cooper 1, and Louis Weinstein 1

1 Department of Medicine, Tufts University School of Medicine, and Pratt Clinic, New England Center Hospital, Boston, Massachusetts

Purified staphylococcal agr-hemolysin (but not the toxoid) was demonstrated on the surface of rabbit and human erythrocytes by immunofluorescence. This occurred during the period of maximal hemolysis and was a transient event. These findings have been analyzed in relation to previous data on the kinetics of leakage of both small and complex molecular constituents of the erythrocyte.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)