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Science 24 July 1964:
Vol. 145. no. 3630, p. 391
DOI: 10.1126/science.145.3630.391
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Articles

Genetics of Isoniazid Metabolism in Caucasian, Negro, and Japanese Populations

Alfred P. Dufour 1, Ralph A. Knight 1, and H. Harris William 1

1 Woman's Medical College of Pennsylvania, Philadelphia 29

Trimodal frequency distributions for isoniazid inactivation were found in Caucasian and Negro populations. The frequency of "rapid" and "slow" alleles in Caucasian and Negro populations was similar and differed from that of a Japanese population.


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