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Science 12 June 1964:
Vol. 144. no. 3624, pp. 1353 - 1354
DOI: 10.1126/science.144.3624.1353

Articles

Lactate Dehydrogenase in Pigeon Testes: Genetic Control by Three Loci

William H. Zinkham 1, Antonio Blanco 1, and Luba Kupchyk 1

1 Department of Pediatrics, Johns Hopkins Hospital, Baltimore 5, Maryland

Homogenates of pigeon testes show three types of lactate dehydrogenase isozyme patterns. Recombination of the polypeptide subunits of the dehydrogenase in mixtures of the different types, and the distribution of the three isozyme patterns in six different pigeon populations demonstrated that lactate dehydrogenase synthesis in pigeon testes is under the control of three distinct loci, A, B, and C.


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