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Science 5 June 1964:
Vol. 144. no. 3623, pp. 1225 - 1226
DOI: 10.1126/science.144.3623.1225

Articles

Monoamine Oxidase Inhibitors: Augmentation of Pressor Effects of Peroral Tyramine

David H. Tedeschi 1 and Edwin J. Fellows 1

1 Department of Neurology and Cardiology, Smith Kline and French Laboratories, Philadelphia 1, Pennsylvania

Monoamine oxidase inhibitors markedly enhance the oral pressor potency of tyramine by preventing it from being destroyed by the monoamine oxidase normally present in liver and intestine. Since certain types of cheese contain high concentrations of tyramine, they should not be eaten by patients during treatment with a monoamine oxidase inhibitor.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Biochemical Correlates of Behavior in Schizophrenic Patients: Schizophrenic Patients Receiving Tryptophan and Methionine or Methionine Together With a Monoamine Oxidase Inhibitor.
H. H. BERLET, K. MATSUMOTO, G. R. PSCHEIDT, J. SPAIDE, C. BULL, and H. E. HIMWICH (1965)
Arch Gen Psychiatry 13, 521-531
   Abstract »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)