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Science 15 May 1964:
Vol. 144. no. 3620, pp. 846 - 849
DOI: 10.1126/science.144.3620.846
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Articles

Immunologically Determined and Competent Cells Are Affected Differentially by Actinomycin D

Eberhardt Weiler 1

1 Institute for Cancer Research, Philadelphia 11, Pennsylvania

A differential effect of actinomycin D on the capacity of mouse peritoneal fluid cells to form antibody after cell transfer has been found. Actinomycin treatment in vitro during transfer inhibited the delayed response toward a first antigen, administered before transfer, while the competence of cells to respond to a second antigen, given aftertransfer, was not affected.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Immunocompetent Cells: Committedness.
D. W. Talmage and E. Weiler (1964)
Science 145, 1073-1074
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Science. ISSN 0036-8075 (print), 1095-9203 (online)