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Science 24 April 1964:
Vol. 144. no. 3617, pp. 417 - 418
DOI: 10.1126/science.144.3617.417
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Articles

Sex-Associated Differences in Serum Proteins of Mice

E. Espinosa 1, E. Canelo 1, M. Bravo 1, and O. González 1

1 Laboratorio de Fisiopatología, Escuela de Medicina y Cátedra de Biología, Escuela de Química y Farmacia, Universidad de Chile, Santiago

Agar electrophoresis of serum from mice of C57BL/10-H-2d, B10.Sn, A.SW, A.CA, R III, and P1 inbred strains shows that the females have a lower concentration of agr-1 serum globulin than the males and, in some strains, the females also have a lower concentration of agr-2 and, beta-serum globulin. Females of the A.SW strain have a higher serum albumin concentration than males, and females of the C57BL/10-H-2d strain have a higher ggr-globulin concentration than males. Two-dimensional (agar and hydrolyzed-starch) electrophoresis gives a typical sex-associated pattern for agr-1 and agr-2 globulins which clearly permits recognition of male and female serums.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)