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Science 10 April 1964:
Vol. 144. no. 3615, pp. 177 - 178
DOI: 10.1126/science.144.3615.177
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Articles

Toxin from Aspergillus flavus: Production on Food Materials of a Substance Causing Tremors in Mice

Benjamin J. Wilson 1 and Christina H. Wilson 2

1 Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, Tennessee
2 Microbiological Research Laboratory, David Lipscomb College, Nashville

A strain of Aspergillus flavus produces, on foodstuffs, a substance which causes tremors and convulsions when administered to mice and certain other animals. The tremorgen, which differs from other recognized toxins attributed to this species, is associated with a distinct, dark spot on thin-layer chromatograms viewed under ultraviolet light.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)