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Science 3 April 1964:
Vol. 144. no. 3614, pp. 65 - 67
DOI: 10.1126/science.144.3614.65
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Articles

Chromosome Number and Morphology of a Human Preinvasive Neoplasm

Ralph M. Richart 1 and Philip A. Corfman 1

1 Departments of Pathology and Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, and Obstetrical and Gynecological Service of the Presbyterian Hospital, New York

The cervical epithelium from five patients with varying degrees of histologically proven intra-epithelial neoplasia can be grown successfully in tissue culture. After four or less successive transfers, the cells are diploid and have a normal karyotype.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Metabolic Controls in Cultured Mammalian Cells: Cultured cells may provide a direct approach to regulation and function in the whole animal.
H. Eagle (1965)
Science 148, 42-51
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Science. ISSN 0036-8075 (print), 1095-9203 (online)