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Science 3 April 1964:
Vol. 144. no. 3614, pp. 57 - 58
DOI: 10.1126/science.144.3614.57
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Articles

Insect Chemosterilants with Low Toxicit for Mammals

Shen Chin Chang 1, Paul H. Terry 1, and Alexej B. Borkovec 1

1 Entomology Research Division, U. S. Department of Agriculture, Beltsville, Maryland

Hexamethylphosphoramide and hexamethylmelamine are effective as male house fly chemosterilants. Both compounds are structurally similar to the two highly active sterilants tepa and tretamine, but they differ from the aziridinyl compounds in their low toxicity for mammals and in their lack of alkylating properties. This discovery of nonalkylating male sterilants of low toxicity should substantially increase the scope and practicality of the sterilemale control method.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Comparative Mutagenicity of Two Chemosterilants, Tepa and Hempa, in Sperm of Bracon hebetor.
J. Palmquist and L. E. Lachance (1966)
Science 154, 915-917
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