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Science 27 March 1964:
Vol. 143. no. 3613, pp. 1443 - 1445
DOI: 10.1126/science.143.3613.1443
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Articles

Homocystinuria: An Enzymatic Defect

S. Harvey Mudd 1, James D. Finkelstein 2, Filadelfo Irreverre 2, and Leonard Laster 2

1 National Institute of Mental Health, Bethesda 14, Maryland
2 National Institute of Arthritis and Metabolic Diseases, Bethesda 14

A deficiency, or absence, of cystathionine synthetase activity has been demonstrated in liver obtained from a mentally retarded child with homocystinuria.


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