Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 27 March 1964:
Vol. 143. no. 3613, pp. 1438 - 1439
DOI: 10.1126/science.143.3613.1438
Prev | Table of Contents | Next

Articles

6-Aminopenicillanic Acid: Inhibition of Destruction of Cephalosporin C by Bacteria

Robert B. Walton 1

1 Merck Sharp & Dohme Research Laboratories, Division of Merck & Co., Inc., Rahway, New Jersey

6-Aminopenicillanic acid, from which all the true penicillins are derived, inhibits the destruction of cephalosporin C by certain microorganisms. This inhibition is probably specific for "cephalosporinase." The enzymatic deacetylation of cephalosporin C is not affected by the acid.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Cephalosporins: Microbiological, Chemical, and Pharmacological Properties and Use in Chemotherapy of Infection.
L. WEINSTEIN and K. KAPLAN (1970)
Ann Intern Med 72, 729-739
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)