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Science Signaling - Call For Papers

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Science 28 February 1964:
Vol. 143. no. 3609, pp. 953 - 954
DOI: 10.1126/science.143.3609.953
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Articles

Radioactive Myoinositol: Incorporation into Streptomycin

Henrik Heding 1

1 Institute of Microbiology, Rutgers University, New Brunswick, New Jersey

Radioactive myoinositol was rapidly incorporated into streptomycin by Streptomyces griseus. All the incorporated radioactivity was found in the streptidine moiety of the antibiotic, as shown by chemical degradation of the streptomycin. To a certain extent inositol reversed the depressing effect of phosphate on the production of the antibiotic.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)