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Science 3 January 1964:
Vol. 143. no. 3601, pp. 46 - 47
DOI: 10.1126/science.143.3601.46
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Articles

Oncogenic Effect of Human Adenovirus Type 12, in Mice

Yoshiro Yabe 1, Luis Samper 1, Estelle Bryan 1, Grant Taylor 1, and John J. Trentin 1

1 Baylor University College of Medicine, and M. D. Anderson Hospital and Tumor Institute, University of Texas, Houston 25

Undifferentiated malignant tumors were induced at the site of injection of human adenovirus type 12 into newborn mice of the C3Hf/ G8. strain, but not of the DBAf, or Af strains. The tumors were grossly and histologically similar to those induced by this virus in hamsters, but appeared in a smaller percentage of injected mice than hamsters.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)