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Science 27 December 1963:
Vol. 142. no. 3600, pp. 1682 - 1683
DOI: 10.1126/science.142.3600.1682
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Articles

Activity Rhythm in Peromyscus: Its Influence on Rates of Recovery from Nembutal

Stephen T. Emlen 1 and William Kem 1

1 Department of Zoology, LUniversity of Michigan, Ann Arbor

Injection of sublethal doses of Nembutal (sodium pentobarbital) into deer mice, Peromyscus maniculatus rufinus (Merriam), at diflerent times in their daily activity cycle revealed large differences in rates of recovery. By taking the phase of the circadian rhythm into account, the accuracy obtained in pharmaceutical and physiological bioassays could be increased.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)