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Science 13 December 1963:
Vol. 142. no. 3598, pp. 1489 - 1490
DOI: 10.1126/science.142.3598.1489
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Articles

Lens Development: Fiber Elongation and Lens Orientation

Jane L. Coulombre 1 and Alfred J. Coulombre 1

1 Laboratory of Neuroanatomical Sciences, National Institute of Neurological Diseases and Blindness, Bethesda 14, Maryland

When the lens of the 5-day chick embryo is surgically reversed so that its epithelium faces the neural retina the elongation of those lens cells which have already differentiated is arrested and the epithelial cells differentiate into a new set of lens fibers. This internal reorganization, together with a reversal in polarity at the lens equator, results in a complete reversal of the polarity of the-entire lens.


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