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Science 27 September 1963:
Vol. 141. no. 3587, pp. 1274 - 1275
DOI: 10.1126/science.141.3587.1274
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Articles

Isolated Mammalian Eye: A Method for Quantitative Evaluation of Autonomic Drugs

William T. Beaver 1

1 Department of Pharmacology, Cornell University Medical College, New York 21

The enucleated rodent eye can be mounted for study in vitro, in a chamber that contains electrodes suitably placed to enable the severed post-ganglionic nerves to the iris to be stimulated. The technique provides a simple quantitative method for the study of drugs which act at the parasympathetic neuro-effector junction.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)