Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 20 September 1963:
Vol. 141. no. 3586, pp. 1181 - 1182
DOI: 10.1126/science.141.3586.1181
Prev | Table of Contents | Next

Articles

Temperature-Dependent Histotypic Changes in Walker Carcinosarcoma in the Chorioallantois

Joseph Leighton 1, Leonard Merkow 1, and Gerald Justh 1

1 Department of Pathology, School of Medicine, University of Pittsburgh Pittsburgh 13, Pennsylvania

Solid tumors grew in the chorioallantois of chick embryos after the topical inoculation of ascites tumor cells. The microscopic character of the growth varied depending on the temperature of incubation. At 32.5°C a sarcomatous appearance was prominent; at 37.5°C carcinomatous structure in several alveolar patterns predominated; at 42.5°C growth was that of a "giant cell" carcinoma.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)