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Science 23 August 1963:
Vol. 141. no. 3582, pp. 726 - 727
DOI: 10.1126/science.141.3582.726

Articles

Antibody Combining Site: The B Polypeptide Chain

O. A. Roholt 1, G. Radzimski 1, and D. Pressman 1

1 Department of Biochemistry Research, Roswell Park Memorial Institute, New York State Department of Health, Buffalo 3

The antibody molecule consists of several polypeptide chains. Peptides, which appear to have been derived from the binding region of the rabbitantibody molecule directed against pazobenzenearsonate, have been isolated. The particular polypeptide chain from which these peptides are derived has now been identified as the B chain described by Fleischman, Pain, and Porter.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A Combinatorial System for Cloning and Expressing the Catalytic Antibody Repertoire in Escherichia coli.
S.A. Iverson, L. Sastry, W.D. Huse, J.A. Sorge, S.J. Benkovic, and R.A. Lerner (1989)
Cold Spring Harb Symp Quant Biol 54, 273-281
   Abstract »    PDF »
Specific Binding Activity of Isolated Light Chains of Antibodies.
T. J. Yoo, O. A. Roholt, and D. Pressman (1967)
Science 157, 707-709
   Abstract »    PDF »
Hapten Binding Activity in Isolated Light Polypeptide Chain from Rabbit Antibody.
T. J. Yoo, O. A. Roholt, and D. Pressman (1967)
Cold Spring Harb Symp Quant Biol 32, 117-118
   Abstract »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)