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Science 9 August 1963:
Vol. 141. no. 3580, pp. 529 - 530
DOI: 10.1126/science.141.3580.529
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Articles

Allergic Encephalomyelitis: Rapid Induction without the Aid of Adjuvants

Seymour Levine 1 and Eugene J. Wenk 1

1 Department of Pathology, St. Francis Hospital, Jersey City, New Jersey

Rapid production of allergic encephalomyelitis has heretofore required injection of nervous tissue emulsified in immunologic adjuvants. Adjuvants are not required if large doses of a potent nervous-tissue anttigen and a highly susceptible strain of rats are used. Susceptibility was increased in animals inoculated beforehand with pertussis vaccine.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Strain Variation in Autoimmunity: Attempted Tolerization of DA Rats Results in the Induction of Experimental Autoimmune Encephalomyelitis.
D. C. Lenz, N. A. Wolf, and R. H. Swanborg (1999)
J. Immunol. 163, 1763-1768
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)