Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 12 July 1963:
Vol. 141. no. 3576, pp. 169 - 171
DOI: 10.1126/science.141.3576.169
Prev | Table of Contents | Next

Articles

Behavioral Response Rates in Pigeons: Effect of agr-Methyl-m-tyrosine

J. N. Hingtgen 1 and M. H. Aprison 1

1 Institute of Psychiatric Research and Departments of Psychiatry and Biochemistry, Indiana University Medical Center, Indianapolis

An intramuscular injection of agr-methyl-m-tyrosine ( 100 mg/ kg), which differentially depletes serotonin and norepinephrine in both brain and heart, was given to two groups of pigeons trained to peck at a key for food. The first group received an injection 12 hours before the daily session and showed no behavioral effect. Response rates of birds in the second group, which were injected 30 minutes after the start of the daily session, decreased and returned to normal within 9 hours after injection. Preliminary data on brain serotonin of pigeons indicate that the disruption of the behavior follows the same time course as the change in serotonin.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Brain Monoamine Oxidase in Mice after Exposure to Aggression and Defeat.
B. E. Eleftheriou and K. W. Boehlke (1967)
Science 155, 1693-1694
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)