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Science 14 June 1963:
Vol. 140. no. 3572, pp. 1219 - 1220
DOI: 10.1126/science.140.3572.1219
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Articles

Antibody Formation in Embryos

Mariano F. La Via 1, David T. Rowlands Jr. 1, and Matthew Block 1

1 Departments of Pathology and Medicine, University of Colorado Medical Center, Denver 20

The production of agglutinins to Salmonella typhi was studied in the opossum embryo in the period immediately before and after the development of thymic and lymph node lymphoid tissue. Antibody was found only in embryos older than 8 days which corresponds to an 8- to 10-week human embryo in terms of organogenesis and is the earliest stage at which antibody production has been recorded.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Ontogeny of the Immune Response.
A. M. Silverstein (1964)
Science 144, 1423-1428
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Science. ISSN 0036-8075 (print), 1095-9203 (online)