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Science 14 June 1963:
Vol. 140. no. 3572, pp. 1218 - 1219
DOI: 10.1126/science.140.3572.1218
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Articles

Individual Antigenic Specificity of Isolated Antibodies

Henry G. Kunkel 1, Mart Mannik 1, and Ralph C. Williams 1

1 Rockefeller Institute, New York 21

Antisera produced against certain isolated human antibodies showed clear antigenic differences between these antibodies. Individual antigenic specificity was demonstrated for two anti-A antibodies, one anti-dextran, and one anti-levan antibody. Failure to produce specific antisera in other instances appeared to be correlated with a greater heterogeneity of the antibody population used as antigen.


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