Antibody Production and Development of Contact Skin Sensitivity in Guinea Pigs of Various Ages
Harold Baer 1 and
Robert T. Bowser 1
1 Division of Biologics Standards, National Institutes of Health, Bethesda 14, Maryland
Young adult guinea pigs, 2 months old, showed higher serum antibody titers and greater contact skin sensitivity than those that had reached the average life-span of 2 to 3 years. A transitional response was given by 6-month-old animals.