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Science 17 May 1963:
Vol. 140. no. 3568, pp. 806 - 808
DOI: 10.1126/science.140.3568.806
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Articles

Strychnine: Its Action on Spinal Motoneurons of Cats

M. G. F. Fuortes 1 and P. G. Nelson 1

1 National Institute of Neurological Diseases and Blindness, Bethesda 14, Maryland

In cats strychnine does not alter measurably the potential, threshold, after potentials, or refractoriness of the membrane of the spinal motoneurons. Increased reflexes probably result from increase of excitatory impingement upon motoneurons. Spikes recorded during a rapid succession of nerve impulses produced by strychnine ("strychnine burst") suggest that soma membrane resistance is appreciable during stimulation.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Strychnine- and Pentylenetetrazol-Induced Changes of Excitability in Aplysia Neurons.
M. R. Klee, D. S. Faber, and W.-D. Heiss (1973)
Science 179, 1133-1136
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Science. ISSN 0036-8075 (print), 1095-9203 (online)