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Science 26 April 1963:
Vol. 140. no. 3565, pp. 400 - 401
DOI: 10.1126/science.140.3565.400
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Articles

Biosynthesis of Streptococcal Cell Walls: A Rhamnose Polysaccharide

L. D. Zeleznick 1, J. J. Boltralik 1, S. S. Barkulis 1, C. Smith 1, and H. Heymann 1

1 Research Department, CIBA Pharmaceutical Company, Summit, New Jersey

Protoplast membranes from Streptococcus pyogenes incorporated rhamnose into a preexisting polysaccharide when incubated with thymidine diphosphate rhamnose-C14. This polysaccharide, when extracted from the membranes, did not give a precipitin reaction with group A antisera, but could be coprecipitated with added group A polysaccharide by acetone. It is presumed to be a precursor to group specific polysaccharide of the streptococcal cell wall.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)