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Science 19 April 1963:
Vol. 140. no. 3564, pp. 316 - 318
DOI: 10.1126/science.140.3564.316
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Articles

Histone and DNA in Isolated Nuclei from Chicken Brain, Liver, and Erythrocytes

Michael B. Sporn 1 and C. Wesley Dingman 1

1 National Institute of Neurological Diseases and Blindness, Bethesda 14, Maryland

In isolated brain and liver nuclei the ratio of histone to deoxyribonucleic acid is lower than in nuclei from erthrocytes. Deoxyribonucleoproteins from brain and liver, in contrast to deoxyribonucleoproteins from erythrocytes, are more soluble in isotonic sodium chloride.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)