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Science 19 April 1963:
Vol. 140. no. 3564, pp. 303 - 304
DOI: 10.1126/science.140.3564.303
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Articles

Hereditary Globulin Factors and Immune Tolerance in Man

Arthur G. Steinberg 1 and Janet A. Wilson 1

1 Department of Biology, Western Reserve University, Cleveland, Ohio

Eight nontransfused donors of antibodies against a hereditary ggr-globulin factor lacked the factor, but each donor's mother had it. The probability that this is a chance observation is .00003. A ninth donor had been transfused, and she and her mother both lacked the factor. It is assumed that each nontransfused donor's antibody was formed against his mother's ggr-globulin and that immune tolerance had not been induced.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Antibody Induction and Tolerance.
O. Smithies (1965)
Science 149, 151-156
   PDF »
Antibody to Hereditary Human Gamma-Globulin (Gm) Factor Resulting from Maternal-Fetal Incompatibility.
H. H. Fudenberg and B. R. Fudenberg (1964)
Science 145, 170-171
   Abstract »    PDF »


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