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Science 19 April 1963:
Vol. 140. no. 3564, pp. 295 - 296
DOI: 10.1126/science.140.3564.295
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Articles

Tarichatoxin: Isolation and Purification

Melancthon S. Brown 1 and Harry S. Mosher 1

1 Department of Chemistry, Stanford University, Palo Alto, California

The potent neurotoxin occurring in the embryos of the California newt, Taricha torosa, has been obtained in crystalline form. With a lethal subcutaneous dose of approximately 0.14 micrograms for a 20-gram mouse, it is, along with saxitoxin and tetrodotoxin, one of the most toxic nonprotein substances known.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Tetrodotoxin: Occurrence in atelopid frogs of Costa Rica.
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F. H. Pough (1971)
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Tarichatoxin-Tetrodotoxin: A Potent Neurotoxin.
H. S. Mosher, F. A. Fuhrman, H. D. Buchwald, and H. G. Fischer (1964)
Science 144, 1100-1110
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Identity of Tarichatoxin and Tetrodotoxin.
H. D. Buchwald, L. Durham, H. G. Fischer, R. Harada, H. S. Mosher, C. Y. Kao, and F. A. Fuhrman (1964)
Science 143, 474-475
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Science. ISSN 0036-8075 (print), 1095-9203 (online)