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Science 9 November 1962:
Vol. 138. no. 3541, pp. 687 - 688
DOI: 10.1126/science.138.3541.687
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Articles

Blood Group A Active Substances in Embryonated Chicken Eggs and Their Relation to Egg-Grown Virus

Georg F. Springer 1 and Harvey Tritel 1

1 Immunochemistry Section, William Pepper Laboratory, and Department of Medical Microbiology, University of Pennsylvania, Philadelphia

Nondialyzable substances similar to blood group A antigens occur in White Leghorn embryos, and in partially purified egg-grown influenza virus preparations. The presence of material with group A activity in the virus itself is not proved. Commercial influenza virus vaccines which were tested contained non-dialyzable substances with group A activity. Injections of this nondialyzable material into human volunteers caused an increase in anti-human blood group A1 and A2 antibodies.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Blood-Group-A-Like Substance in a Preparation of Pneumococcal Vaccine.
G. R. SIBER, D. M. AMBROSINO, and B. C. GORGONE (1982)
Ann Intern Med 96, 580-586
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