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Science 26 October 1962:
Vol. 138. no. 3539, pp. 519 - 520
DOI: 10.1126/science.138.3539.519
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Articles

Maintenance of Globulin Levels in X-irradiated Rabbits after Immunization

Marvin B. Rittenberg 1 and Eric L. Nelson 1

1 Department of Bacteriology, University of California, Los Angeles

Rabbits were injected with antigen 24 hours after x-irradiation. Antibody titers were correlated with relative changes in gamma-beta globulin levels determined electrophoretically. Irradiated, immunized rabbits did not form detectable antibodies but had significantly greater globulin levels than non-immunized, irradiated controls. This relative difference occurred at the time nonirradiated, immunized rabbits were producing primary antibody.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)