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Science 26 October 1962:
Vol. 138. no. 3539, pp. 509 - 510
DOI: 10.1126/science.138.3539.509
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Articles

Lactic and Malic Dehydrogenases in Human Fetal Tissues

B. Wiggert 1 and C. A. Villee 1

1 Department of Biological Chemistry, Harvard Medical School, and Research Laboratories, Boston Lying-in Hospital, Boston, Massachusetts

The nonparticulate fraction of homogenates of heart, liver, kidney, lung, and cerebral cortex from human fetuses of varying gestational ages was subjected to electrophoresis on starch grains. Five lactic dehydrogenases and two malic dehydrogenases with characteristic rates with pyridine nucleotide analogs were found in all tissues at all ages. Quantitative differences in the relative proportions of these peaks were observed as gestation proceeded.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Malic Dehydrogenase Isozymes: Distribution in Developing Nucleate and Anucleate Halves of Sea Urchin Eggs.
G. W. Patton Jr., L. Mets, and C. A. Villee (1967)
Science 156, 400-401
   Abstract »    PDF »
Malate Dehydrogenase: Multiple Forms in Separated Blastomeres of Sea Urchin Embryos.
R. O. Moore and C. A. Villee (1963)
Science 142, 389-390
   Abstract »    PDF »
Malic Dehyrogenases in Sea Urchin Eggs.
R. O. Moore and C. A. Villee (1962)
Science 138, 508-509
   Abstract »    PDF »


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