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Science 7 September 1962:
Vol. 137. no. 3532, pp. 762 - 763
DOI: 10.1126/science.137.3532.762
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Articles

Mechanism of Tissue Reconstruction by Dissociated Cells, II: Time-Course of Events

Malcolm S. Steinberg 1

1 Department of Biology, Johns Hopkins University, Baltimore 18, Maryland

The details of the process by which cells sort out and reconstruct tissues within aggregates containing two kinds of tissue cells have been correctly predicted from considerations of the kinetic and adhesive properties of such cells. The requisite properties are discreteness, motility, and differential mutual adhesiveness among the types of cells present.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)