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Science 9 June 1961:
Vol. 133. no. 3467, pp. 1829 - 1830
DOI: 10.1126/science.133.3467.1829
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Articles

Instrumental Conditioning of Jugular Self-Infusion in the Rhesus Monkey

Robert Clark 1, Charles R. Schuster 1, and Joseph V. Brady 1

1 Walter Reed Army Institute of Research, Washington, D.C., and Laboratory of Psychopharmacology, University of Maryland, College Park

A technique is described for self-infusion of pharmacologic agents in solution through a permanently indwelling jugular catheter in the rhesus monkey. The results of an experiment utilizing this technique demonstrate that an instrumental lever response can be conditioned, extinguished, reconditioned, and brought under stimulus control and reward-schedule control with saline self-infusion as the reinforcing stimulus.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Control theory and feeding.
M. Toates (1983)
Transactions of the Institute of Measurement and Control 5, 48-56
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Science. ISSN 0036-8075 (print), 1095-9203 (online)