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Science 13 January 1961:
Vol. 133. no. 3446, pp. 99 - 100
DOI: 10.1126/science.133.3446.99
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Articles

Facilitation of Infection of Monkey Cells with Poliovirus "Ribonucleic Acid"

George R. Dubes 1 and Eugene A. Klingler Jr. 1

1 Section of Virus Research, Department of Pediatrics, University of Kansas School of Medicine, Kansas City

The plaque titer of poliovirus "ribonucleic acid" on monkey kidney cells cultured in vitro is greatly increased by depleting these cells of calcium and treating the "ribonucleic acid" inoculum with a suspension of any one of several poorly water-soluble substances before inoculation. These undissolved substances apparently facilitate infection by serving as solid vehicles for the "ribonucleic acid."


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Uptake of Protein by Mammalian Cells: An Underdeveloped Area: The penetration of foreign proteins into mammalian cells can be measured and their functions explored.
H. J.-P. Ryser (1968)
Science 159, 390-396
   Abstract »    PDF »
Physical and Chemical Properties and Infectivity of RNA from Animal Viruses.
F. L. Schaffer (1962)
Cold Spring Harb Symp Quant Biol 27, 89-99
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)