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Science 6 January 1961:
Vol. 133. no. 3445, pp. 44 - 45
DOI: 10.1126/science.133.3445.44
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Articles

Excessive Stimulation of Salivary Gland Growth by Isoproterenol

Hans Selye 1, Rene Veilleux 1, and Marc Cantin 1

1 Institut de Médecine et de Chirurgie expérimentales, Université de Montréal, Montreal, Canada

In the rat, chronic treatment with isoproterenol can cause a selective growth of the salivary glands to approximately five times their normal size within 17 days. This enlargement is principally due to mitotic proliferation and hypertrophy of the parenchymatous cells.


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