Effect of Reserpine on Ventricular Escape
Jay Roberts 1 and
Richard P. Stadter 1
1 Department of Pharmacology, Cornell University Medical College, New York, New York
Catecholamine depletion by reserpine diminishes the tendency of the ventricle to escape from vagal suppression. Neither spinal section nor adrenalectomy enhances the reserpine effect. Norepinephrine restores the characteristic occurrence of ventricle escape during vagal stimulation.