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Science 11 November 1960:
Vol. 132. no. 3437, pp. 1398 - 1399
DOI: 10.1126/science.132.3437.1398
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Articles

Specific Inhibition of RHO(D) Antibody by Sialic Acids

Matthew C. Dodd 1, Nancy J. Bigley 1, and Virginia B. Geyer 1

1 Department of Bacteriology, Ohio State University, Columbus

Agglutination of RhO(D) erythrocytes by specific antiserum was inhibited by crude and crystalline N-acetylneuraminic acid, less inhibited by its glycoyl derivative, and weakly inhibited by its degradation product, N-acetyl-mannosamine, and by D-mannose. A brain ganglioside containing neuraminic acid and a Pseudomonas polysaccharide were even more inhibitory. Inhibition was specific for anti-D sera.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Blood-Group Substances.
W. M. Watkins (1966)
Science 152, 172-181
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Science. ISSN 0036-8075 (print), 1095-9203 (online)