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Science 28 October 1960:
Vol. 132. no. 3435, pp. 1249 - 1250
DOI: 10.1126/science.132.3435.1249
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Articles

Acetylcholinesterase Regeneration in Peripheral Nerve after Irreversible Inactivation

Edward Koenig 1 and George B. Koelle 1

1 Department of Pharmacology and Institute of Neurological Sciences, University of Pennsylvania Schools of Medicine, Philadelphia

The return of acetylcholinesterase activity was studied in several cholinergic structures in the cat after irreversible inactivation by diisopropylfluoro-phosphate. It was found that enzymic activity returned uniformly along the hypoglossal and cervical sympathetic nerve trunks. No evidence for somatoaxonal convection of enzyme was obtained.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Local Gene Expression in Axons and Nerve Endings: The Glia-Neuron Unit.
A. Giuditta, J. Tai Chun, M. Eyman, C. Cefaliello, A. P. Bruno, and M. Crispino (2008)
Physiol Rev 88, 515-555
   Abstract »    Full Text »    PDF »
Migration of Proteins along the Axons of the Sciatic Nerve.
B. Droz and C. P. Leblond (1962)
Science 137, 1047-1048
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)