Increased Incidence of Tumor Metastases in Female Mice
Renato Baserga 1 and
Walter E. Kisieleski 1
1 Department of Pathology, Northwestern University Medical Schlool, Chlicago, Illinois, and Argonne National Laboratory, Argonne, Illinois
Most of the tumor cells injected into the tail vein of mice fail to survive at the site of arrest in the lungs, but the percentage of surviving cells is higher in females than in males. The surviving cells, however, grow at a similar and constant rate in both sexes.