Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 2 September 1960:
Vol. 132. no. 3427, pp. 621 - 622
DOI: 10.1126/science.132.3427.621
Prev | Table of Contents | Next

Articles

Dehydrogenase Activities in Dystrophic Mice

M. W. McCaman 1

1 Institute of Psychiatric Research, and Department of Neurology, Indiana University Medical Center, Indianapolis

The levels of activity of glucose-6-phosphate dehydrogenase, isocitric dehydrogenase, glutathione reductase, lactic dehydrogenase, and a-glycerophosphate dehydrogenase have been studied in the gastrocnemius muscle of mice with "dystrophia muscularis." The activity of enzymes requiring triphosphopyridine nucleotide as a cofactor is increased relative to the control littermates, whereas the activity of those enzymes requiring diphosphopyridine nucleotide is decreased.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cytochemical Localization of Lactate Dehydrogenase in Muscular Dystrophy of the Mouse.
H. D. Fahimi and P. Roy (1966)
Science 152, 1761-1763
   Abstract »    PDF »
Bioelectric Properties of Dystrophic Mammalian Muscle: Excitability, Membrane Resting, and Action Potentials in Mouse Hereditary Myopathy.
J. T. CONRAD and G. H. GLASER (1961)
Arch Neurol 5, 46-59
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)