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Science 13 May 1960:
Vol. 131. no. 3411, p. 1441
DOI: 10.1126/science.131.3411.1441
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Articles

Disulfide Interchange by Ionizing Radiation

D. Cavallini 1, B. Mondovi 1, B. Giovanella 1, and C. De Marco 1

1 Intitutes of Biological Chemistry of the Universities of Modena and Rome and Regina Elena Institute for Cancer Research, Rome, Italy

The irradiation of a soluition of two symmetric disulfides produces detectable amounts of the nonsymmetric mixed disulfide. The effect is abolished by the addition of ethylmaleimide. The finding indicates that radiation caulses a disulfide opening and recombining process which may be of radiobiological interest.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)