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Science 19 February 1960:
Vol. 131. no. 3399, pp. 500 - 501
DOI: 10.1126/science.131.3399.500

Articles

Separation of Serum Antibody Activities by Anion-Exchange Cellulose Chromatography

John L. Fahey 1

1 National Cancer Institute, Bethesda, Maryland

Mumps, Histoplasma capsulatum. thyroglobulin, and typhoid H antibodies were found in fraction 1, which contained only gamma globulins with ultracentrifugal sedimentation coefficients of 6.6 Svedberg units (S). Typhoid O antibodies and rheumatoid factor were only in fraction 5, composed principally of gamma macroglobulins with ultracentrifugal sedimentation coefficients of 18 S. In contrast isohemagglutinins, Rh antibodies, and anti-human liver nucleoprotein activities were found in two chromatogram fractions (1 and 5) with different physicochemical properties.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Three ggr-Globulins in Normal Human Serum Revealed by Monkey Precipitins.
S. Dray (1960)
Science 132, 1313-1314
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