Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 27 November 1959:
Vol. 130. no. 3387, p. 1472
DOI: 10.1126/science.130.3387.1472
Prev | Table of Contents | Next

Articles

Serological Procedure for the Detection of Antibodies to Penicillin

MARGUERITE EPP 1

1 Department of Bacteriology, University of Saskatchewan, Saskatoon, Canada

A hemagglutination technique for demonstrating antibodies to penicillin in sera from penicillin-allergic subjects is described. Erythrocytes coupled to penicillin T by means of bis-diazotized-benzidine constitute the "antigen" used to measure the antipenicillin antibody. The hemagglutination reaction is highly specific. as indicated by hemagglutination-inhibition studies. The clinical significance of these antibodies remains to be elucidated.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Acquired Hemolytic Anemia and Antipenicillin Antibody: Case Report and Review of Literature.
P. V. STRUMIA and F. D. RAYMOND (1962)
Arch Intern Med 109, 603-608
   Abstract »    PDF »
Detecting Antibodies to Penicillin.
M. S. Mallen (1960)
Science 131, 1402
   PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)