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Science 2 October 1959:
Vol. 130. no. 3379, pp. 861 - 862
DOI: 10.1126/science.130.3379.861
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Articles

Protection by Sulfur Compounds against the Air Pollutants Ozone and Nitrogen Dioxide

EDWARD J. FAIRCHILD II 1, SHELDON D. MURPHY 1, and HERBERT E. STOKINGER 1

1 Occupational Health Program, U.S. Public Health Service, Cincinnati, Ohio

Two distinct but related pathways of protection against the lethal effects of ozone and nitrogen dioxide are shown by (i) simultaneous inhalation of compounds that furnish —SH or —SS—, or both, and (ii) by injection of thiourea derivatives several days prior to exposure to these oxidant gases. The mechanism of (i) is believed similar to that proposed for the action of radiation-protective compounds; that of (ii) involves the development of a tolerance initiated by the thiourea against the oxidants.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Pulmonary Protein Synthesis Response to Ozone.
F.J. Kelly and S. Birch (1994)
Human and Experimental Toxicology 13, 407-410
   Abstract »    PDF »
Silo-Filler's Disease: Nitrogen Dioxide-Induced Lung Injury: Long-Term Follow-up and Review of the Literature.
J. RAMlREZ-R. and A. R. DOWELL (1971)
Ann Intern Med 74, 569-576
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)