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Science 11 September 1959:
Vol. 130. no. 3376, pp. 626 - 627
DOI: 10.1126/science.130.3376.626
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Articles

Immunization of Mice against Toxic Doses of Homologous Elementary Bodies of Trachoma

SAMUEL D. BELL JR. 1, JOHN C. SNYDER 1, and EDWARD S. MURRAY 1

1 Department of Microbiology, Harvard School of Public Health, Boston, Massachusetts

Death of mice occurs 2 to 8 hours after intravenous inoculation of concentrated viable elementary bodies of trachoma. Toxic death can be prevented by vaccinating the mice with concentrated suspensions of homologous strains inactivated by formalin or phenol. Judged by toxic challenges, at least two antigenically distinct types of elementary bodies of trachoma occur in Saudi Arabia and Egypt.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Experimental Inclusion Conjunctivitis in Man: Measurements of Infectivity and Resistance.
E. Jawetz, L. Rose, L. Hanna, and P. Thygeson (1965)
JAMA 194, 620-632
   Abstract »    PDF »
TRACHOMA-STUDIES OF ETIOLOGY, LABORATORY DIAGNOSIS, AND PREVENTION.
J. T. Grayston, S.-P. Wang, R. L. Woolridge, Y.-F. Yang, and P. B. Johnston (1960)
JAMA 172, 1577-1586
   Abstract »    PDF »
Morphologic Observations on Trachoma Virus in Cell Cultures.
F. B. Gordon, A. L. Quan, and R. W. Trimmer (1960)
Science 131, 733-734
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)