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Science 24 July 1959:
Vol. 130. no. 3369, p. 217
DOI: 10.1126/science.130.3369.217
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Articles

Density-Gradient Centrifugation with Infectious Ribonucleic Acid of Foot-and-Mouth Disease Virus

K. STROHMAIER 1 and M. MUSSGAY 1

1 Federal Research Institute for Animal Virus Diseases, Tübingen, Germany

The sedimentation constant of an infectious component in ribonucleic acid preparations from foot-and-mouth disease virus has been determined by density-gradient centrifugation. A sedimentation constant of 37 Svedberg units (St) was obtained. On the assumption that the relation between the molecular weight and the sedimentation constant found by Gierer is applicable to our system as well, a value of 3.1 x 106 was calculated for the molecular weight of the infectious component.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Physical and Chemical Properties and Infectivity of RNA from Animal Viruses.
F. L. Schaffer (1962)
Cold Spring Harb Symp Quant Biol 27, 89-99
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Science. ISSN 0036-8075 (print), 1095-9203 (online)