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Science 3 July 1959:
Vol. 130. no. 3366, pp. 41 - 42
DOI: 10.1126/science.130.3366.41
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Articles

Adsorption of Antibody in vitro and Magnitude of the Schultz-Dale Reaction of Guinea-Pig Ileum

C. B. NIELSEN 1, GERONIMO TERRES 2, and GEORGE A. FEIGEN 1

1 Department of Physiology, Stanford University, Stanford, California
2 Brookhaven National Laboratory, Upton, Long Island, New York

Studies show that the adsorption of rabbit antiovalbumin-I131 on guinea-pig ileum conforms to a Langmuirian isotherm, and that the physiological response to challenge with antigen depends upon the amount of antibody bound to the tissue.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)